Nuklearmedizin 2001: 90Y-DOTATOC - Erfolgreiche Therapie maligner neuroendokriner Tumore

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Biokinetic and Dosimetry of 90y-dotatoc Therapy for Neuroendocrine Tumours

Biokinetic model is a mathematical model which describes the behavior of the Y in human body during the treatment of neuroendocrine tumours. This paper presents calculation of absorbed doses in human organs in biokinetic model Y for DOTATOC therapy. For this purpose, the human body is represented by five compartments: blood, kidneys, urinary bladder, tumour and liver. The input file was develop...

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Semi-automatic 3D-volumetry of liver metastases from neuroendocrine tumors to improve combination therapy with 177Lu-DOTATOC and 90Y-DOTATOC.

PURPOSE Patients with neuroendocrine tumors (NET) often present with disseminated liver metastases and can be treated with a number of different nuclides or nuclide combinations in peptide receptor radionuclide therapy (PRRT) depending on tumor load and lesion diameter. For quantification of disseminated liver lesions, semi-automatic lesion detection is helpful to determine tumor burden and tum...

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90Y-DOTATOC as a Therapeutic Option for Complex Recurrent or Progressive Meningiomas.

UNLABELLED The standard treatment of meningiomas is surgery or radiotherapy. Complex, especially recurrent or progressive cases, may exhibit tumor growth involving critical neurovascular structures or diffuse growth, resulting in limited efficacy and higher risk of standard treatment. We evaluated whether somatostatin receptor-targeted radionuclide therapy with (90)Y-DOTATOC may be a therapeuti...

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Targeted radionuclide therapy with 90Y-DOTATOC in patients with neuroendocrine tumors.

BACKGROUND The aim of this study was to assess the efficacy and safety of targeted radionuclide therapy with [90Y-DOTA0, Tyr3]-octreotide (90Y-DOTATOC) in patients with metastatic neuroendocrine tumors. PATIENTS AND METHODS One hundred and sixteen patients with metastatic neuroendocrine tumors were included. All patients were pre-therapeutically staged with morphological imaging procedures an...

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Nuklearmedizin in Der Klinik

Steroids, is another significant contribution. In the opinion of this reviewer, it is the best book in the field. It has been written by a hand that understands the theory of chromatography, yet is fissured by personal contact with solvents. The book has been well planned. At the beginning is a glossary, perhaps unduly complicated. This is followed by thirty pages of the theory of chromatograph...

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ژورنال

عنوان ژورنال: Swiss Medical Forum ‒ Schweizerisches Medizin-Forum

سال: 2002

ISSN: 1424-4020,1424-3784

DOI: 10.4414/smf.2002.04391